ScholarLens Back to search
2006•OrganometallicsRequires access

Efficient Redox Isomerization of Allylic Alcohols under Mild Conditions Catalyzed by Arene−Ruthenium(II) Complexes

Pascale Crochet, M.A. Fernandez-Zumel, José Gimeno, Marcus Scheele

Open publisher page 62 citations

Abstract

The catalytic activity of the arene−ruthenium(II) complexes [RuCl 2 (η 6 - p -cymene)(L)] (L = P(OPh) 3, P(OMe) 3, P(OEt) 3, PPh 3, P( p -C 6 H 4 OMe) 3, PMe 2 Ph, PMe 3, PEt 3, PCy 3 ) in the isomerization of allylic alcohols into the corresponding saturated ketones has been investigated, the best performances being obtained using [RuCl 2 (η 6 - p -cymene){P(OEt) 3 }]. This compound has proven to be able to catalyze the transformation of poorly reactive substrates of the type R 1 CH CHCH(OH)R 2 and R 1 CH C(R 2 )CH(OH)R 3 (R 1, R 2, R 3 ≠ H) under very smooth conditions.

About this research paper

What this paper is about

The catalytic activity of the arene−ruthenium(II) complexes [RuCl 2 (η 6 - p -cymene)(L)] (L = P(OPh) 3, P(OMe) 3, P(OEt) 3, PPh 3, P( p -C 6 H 4 OMe) 3, PMe 2 Ph, PMe 3, PEt 3, PCy 3 ) in the isomerization of allylic alcohols into the corresponding saturated ketones has been investigated, the best performances being obtained using [RuCl 2 (η 6 - p -cymene){P(OEt) 3 }]. This compound has proven to be able to catalyze the transformation of poorly reactive substrates of the type R 1 CH CHCH(OH)R 2 and R 1 CH C(R 2 )CH(OH)R 3 (R 1, R 2, R 3 ≠ H) under very smooth conditions.

Why it matters

OpenAlex reports 62 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The catalytic activity of the arene−ruthenium(II) complexes [RuCl 2 (η 6 - p -cymene)(L)] (L = P(OPh) 3, P(OMe) 3, P(OEt) 3, PPh 3, P( p -C 6 H 4 OMe) 3, PMe 2 Ph, PMe 3, PEt 3, PCy 3 ) in the isomerization of allylic alcohols into the corresponding saturated ketones has been investigated, the best performances being obtained using [RuCl 2 (η 6 - p -cymene){P(OEt) 3 }]. This compound has proven to be able to catalyze the transformation of poorly reactive substrates of the type R 1 CH CHCH(OH)R 2 and R 1 CH C(R 2 )CH(OH)R 3 (R 1, R 2, R 3 ≠ H) under very smooth conditions.

Key concepts: Chemistry, Isomerization, Ruthenium, Allylic rearrangement, Catalysis, Medicinal chemistry, Redox, Stereochemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Efficient Redox Isomerization of Allylic Alcohols under Mild Conditions Catalyzed by Arene−Ruthenium(II) Complexes — Research Paper | ScholarLens