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Asymmetric Reduction of Acetophenone with Borane Catalyzed by Chiral Oxazaborolidinones Derived from L-α-Amino Acids

Shi‐Wen Huang, Bo Wang, Zixing Shan, Dejie Zhao

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Abstract

Some chiral oxazaborolidinones were prepared from L-α-amino acids reacting with borane and used as a new type of catalysts for asymmetric reduction of acetophenone with borane to afford R-(+)-1-phenyl ethanol with 23–76%ee in high yield.

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What this paper is about

Some chiral oxazaborolidinones were prepared from L-α-amino acids reacting with borane and used as a new type of catalysts for asymmetric reduction of acetophenone with borane to afford R-(+)-1-phenyl ethanol with 23–76%ee in high yield.

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OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Some chiral oxazaborolidinones were prepared from L-α-amino acids reacting with borane and used as a new type of catalysts for asymmetric reduction of acetophenone with borane to afford R-(+)-1-phenyl ethanol with 23–76%ee in high yield.

Key concepts: Acetophenone, Chemistry, Borane, Catalysis, Yield (engineering), Ethanol, Organic chemistry, Amino acid

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Asymmetric Reduction of Acetophenone with Borane Catalyzed by Chiral Oxazaborolidinones Derived from L-α-Amino Acids — Research Paper | ScholarLens