ScholarLens Back to search
1995•PubMedRequires access

Synthesis and pharmacology of two new histamine receptor antagonists related to ranitidine.

Jean-Philippe Navarro, Jesús F. Almeida, Josefa Anaya, Joaquı́n R. Morán, Marco Grande, M. C. CABALLERO, B. Palacios, María J. Montero, Luís San Román

Open publisher page 3 citations

Abstract

Pyridyl and 1,6-dihydropyridyl ranitidine analogues 1 and 2 were obtained by applying an improved modification of ranitidine synthesis. Compound 1 shows a selective H2 antagonistic activity while compound 2 is a non-selective histamine antagonist.

About this research paper

What this paper is about

Pyridyl and 1,6-dihydropyridyl ranitidine analogues 1 and 2 were obtained by applying an improved modification of ranitidine synthesis. Compound 1 shows a selective H2 antagonistic activity while compound 2 is a non-selective histamine antagonist.

Why it matters

OpenAlex reports 3 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Pyridyl and 1,6-dihydropyridyl ranitidine analogues 1 and 2 were obtained by applying an improved modification of ranitidine synthesis. Compound 1 shows a selective H2 antagonistic activity while compound 2 is a non-selective histamine antagonist.

Key concepts: Ranitidine, Histamine, Antagonist, Pharmacology, Chemistry, Histamine H2 receptor, Receptor, Medicine

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Synthesis and pharmacology of two new histamine receptor antagonists related to ranitidine. — Research Paper | ScholarLens