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Total Artificial Heart as the Destination Therapy: A Review

Abdul Mannan Khan Minhas, Salman Assad, Maryam Khan, Saba Ahmed, Muhammad Shahzeb Khan, Sriharsha Chakravarthi Athota, Jonathan Constantin

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Abstract

Introduction: For the patients awaiting cardiac transplantation, mechanical circulatory support has been widely utilized in the form of left ventricular assist device or total artificial heart. Both total artificial heart and left ventricular assist device have been approved for the use as a bridge to transplantation therapy; however only left ventricular assist device has been approved for use as the destination therapy. The purpose of this review is to establish, using this literature, the possibility for the artificial heart transplant to be used as destination therapy besides highlighting the recent developments in this area of research in order to narrate the future of artificial heart transplantation. You can submit your Manuscripts at: https://symbiosisonlinepublishing.com/submitManuscript.php

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Key concepts: Artificial heart, Destination therapy, Bridge to transplantation, Heart transplantation, Ventricular assist device, Medicine, Transplantation, Bridge (graph theory)