IgG responses to intranasal immunization with cholera-toxin-immobilized polymeric nanospheres in mice

Polymeric nanospheres (NS) have a wide potential in the manufacture of biomedical wares [1, 2], optical devices [3] and other industrial materials [4] because of their extremely large surface area to volume ratios. Various substances from metal ions *To whom correspondence should be addressed at Osaka University. E-mail: akashi@chem.eng.osaka-u.ac.jp 76 T. Kaneko et al.