Effect of vıtamın E and selenium on performance, plasma and tissue GSH-PX Activity in broilers

The aim of this study was to determine the effectsof Vitamin E and organic or inorganic selenium sources combined with Vitamin Eon growth performance and plasma and tissue glutathione peroxidase activity inbroilers. A total of 168, one-day old female commercial broiler chicks (Hubbardstrain) were randomly allotted to one control and three treatment groups, eachcontaining 42 birds. All experimental groups were replicated three times with14 chicks per replicate. Feed and water were supplied ad libitum during theexperimental period. Four experimental diets were provided as follows: a. Basaldiet without Vitamin E and any selenium sources, for the control group(control). b. Basal diet supplemented with 250 mg/kg Vitamin E for thetreatment group 1 (Vit E). c. Basal diet supplemented with 250 mg/kg Vitamin Eplus 0.2 mg/kg organic selenium for the treatment group 2 (Vit E+Or Se) d.Basal diet supplemented with 250 mg/kg Vitamin E, plus 0.2 mg/kg inorganicselenium for the treatment group 3 (Vit E+Inor Se). The experiment lasted 42days At the end of the study, there was a difference (P<0.05) regarding bodyweight gain in the first (Vit E) and the second (Vit E+Or Se) treatment groupscompared to the control group. Feedconversion ratio was more efficient (P<0.05) in the treatment group 2 (VitE+Or Se) compared to the rest. Glutathione peroxidase activity in plasma(P<0.01), kidney (P<0.05), leg muscle (p<0.05), heart (P<0.01) andliver (P<0.01) elevated in all of the treatment groups compared to thecontrol group. Liver glutathione peroxidase activity in the treatment group 2(Vit E+Or Se) was higher than the rest. The results of this study indicatedthat, utilisation of organic selenium plus vitamin E in broiler diets waseffective for improving the body weight gain, the feed conversion ratio, andplasma and tissue glutathione peroxidase activity