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A Novel Synthesis of 3-Substituted Indazole Derivatives

Willard M. Welch, Catherine E. Hanau, William M. Whalen

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Abstract

All articles of this category The dianion prepared from 3-bromo-1 H -indazole and alkyllithium bases reacts with a variety of electrophiles to give the corresponding 3-monosubstituted 1 H -indazole derivatives in moderate yields. This procedure is more general and shorter than earlier methods.

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What this paper is about

All articles of this category The dianion prepared from 3-bromo-1 H -indazole and alkyllithium bases reacts with a variety of electrophiles to give the corresponding 3-monosubstituted 1 H -indazole derivatives in moderate yields. This procedure is more general and shorter than earlier methods.

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OpenAlex reports 29 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

All articles of this category The dianion prepared from 3-bromo-1 H -indazole and alkyllithium bases reacts with a variety of electrophiles to give the corresponding 3-monosubstituted 1 H -indazole derivatives in moderate yields. This procedure is more general and shorter than earlier methods.

Key concepts: Indazole, Chemistry, Electrophile, Combinatorial chemistry, Medicinal chemistry, Organic chemistry, Catalysis

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