2016•ChemInformRequires access
ChemInform Abstract: Regioselective Dihydropyran Formation from 4‐Iodo‐2,6‐disubstituted Tetrahydropyran Derivatives Using In(OAc)3/LiI System as the Promoter.
Thibaut Chalopin, Khaoula Jebali, Catherine Gaulon‐Nourry, F. Dénès, Jacques Lebreton, Monique Mathé‐Allainmat
Open publisher page 0 citations
Abstract
Abstract Starting from 2‐substituted homoallyl alcohols and various aldehydes a diastereomeric mixture of 2,6‐disubstituted 4‐iodotetrahydropyrans is prepared, and the products are further subjected to the regioselective elimination to form dihydropyran derivatives with an ether functionality in position 6.