1998The Review of High Pressure Science and TechnologyOpen access

Organic Reactions and High Pressure. Organic Reactions at High Pressure.

Frank‐Gerrit Klärner, Frank Wurche

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Abstract

The utility of high pressure for the understanding of chemical reactions and its applications in organic synthesis is demonstrated for pericyclic reactions (cycloadditions, Cope rearrangements, electrocyclizations and intramolecular Diels-Alder reactions).With the example of the peptide coupling it is shown that pressure is a valuable tool for the control of other reactions than pericyclic reactions, too.

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The utility of high pressure for the understanding of chemical reactions and its applications in organic synthesis is demonstrated for pericyclic reactions (cycloadditions, Cope rearrangements, electrocyclizations and intramolecular Diels-Alder reactions).With the example of the peptide coupling it is shown that pressure is a valuable tool for the control of other reactions than pericyclic reactions, too.

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Available abstract

The utility of high pressure for the understanding of chemical reactions and its applications in organic synthesis is demonstrated for pericyclic reactions (cycloadditions, Cope rearrangements, electrocyclizations and intramolecular Diels-Alder reactions).With the example of the peptide coupling it is shown that pressure is a valuable tool for the control of other reactions than pericyclic reactions, too.

Key concepts: Pericyclic reaction, Intramolecular force, Organic reaction, Chemistry, High pressure, Coupling reaction, Computational chemistry, Organic synthesis

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