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Isolation and Analysis of Antibiotic Compounds from Soil Microbes

Colin Hunter Harrington, Matthew Ross Googins, Parsant Jotikasthira

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Abstract

The growing number of antibiotic resistant strains of bacteria is a serious issue that must be addressed. New antibiotics need to be found to prevent a global epidemic. Soil bacteria isolates from the Microbes to Molecules (BB2905) course were identified and their products were purified and analyzed. We developed an identification pipeline for antibiotic discovery to proceed from the BB2905 course. We extracted and analyzed an antibiotic extract from two of the bacterial isolates using this pipeline.

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The growing number of antibiotic resistant strains of bacteria is a serious issue that must be addressed. New antibiotics need to be found to prevent a global epidemic. Soil bacteria isolates from the Microbes to Molecules (BB2905) course were identified and their products were purified and analyzed. We developed an identification pipeline for antibiotic discovery to proceed from the BB2905 course. We extracted and analyzed an antibiotic extract from two of the bacterial isolates using this pipeline.

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Available abstract

The growing number of antibiotic resistant strains of bacteria is a serious issue that must be addressed. New antibiotics need to be found to prevent a global epidemic. Soil bacteria isolates from the Microbes to Molecules (BB2905) course were identified and their products were purified and analyzed. We developed an identification pipeline for antibiotic discovery to proceed from the BB2905 course. We extracted and analyzed an antibiotic extract from two of the bacterial isolates using this pipeline.

Key concepts: Isolation (microbiology), Antibiotics, Microbiology, Biology

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