The Clinopathological Profile of Pediatric Patients with Pancytopenia In Vadodara

Introduction: Pancytopenia is a key clinico-hematological thing comes across in day-to-day meidcal practice. It is a situation dealing with decrease in red blood cells (RBCs), white blood cells (WBCs) and platelets and usually suspected medically with finding of unsolved pallor. Careful check-up of a blood is important if cause for the pancytopenia does not seem from the medical history. If blood examination will not reveal cause then bone marrow aspiration and trephine are of use. Materials and methods: Present study was retrospective in nature and was carried out at Dhiraj General Hospital, Sumandeep Vidyapeeth, Vadodara from January 2014 to December 2015 for period of 2 years. All pediatric patients who came to hospital were became part of present study and undergone necessary investigations like complete blood count (CBC), peripheral smear (PS) examination, bone marrow aspiration and bone marrow trephine biopsy etc. Results: Among 200 pediatric patients, most common age group was ranged from 1 month to 6 years. Megaloblastic anemia (29%) followed by Aplastic anemia (15.0%) found to be reason for pancytopenia whereas 21.5% of pediatric patients showed leukemia as a reason for pancytopenia. Pallor was found to be most common symptoms in about 170 (85%) patients and fever was in 123 (61.5%) patients. Conclusion: Megaloblastic anemia followed by acute leukemia and aplastic anemia are routine causes encountered for pancytopenia in our study.