An Exploratory Study of the Combination of Monoclonal Antibodies Alemtuzumab and Rituximab in the Treatment of CD52- and CD20-Positive Chronic Lymphoid Disorders
Susan O’Brien
Abstract
Susan O’Brien
Abstract
Monoclonal antibodies demonstrate impressive response rates in lymphoid diseases, and treatment indications are expanding. Both alemtuzumab (Campath) (anti-CD52) and rituximab (Rituxan) (anti-CD20) are active in chronic lymphocytic leukemia (CLL) and low-grade lymphomas.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Monoclonal antibodies demonstrate impressive response rates in lymphoid diseases, and treatment indications are expanding. Both alemtuzumab (Campath) (anti-CD52) and rituximab (Rituxan) (anti-CD20) are active in chronic lymphocytic leukemia (CLL) and low-grade lymphomas.
Key concepts: CD52, Alemtuzumab, Chronic lymphocytic leukemia, Rituximab, CD20, Monoclonal antibody, Medicine, Ofatumumab