Evaluation of Subgingival Application of 1.5% Zanthane Based Chlorhexidine Gel in Chronic Periodontitis Patients

Introduction: Today, a variety of materials and techniques are used as a supplement of scaling and root planing for treatment of periodontal diseases. This study examined the clinical efficacy of zanthane base chlorhexidine gel (Chlo-site) as adjunctive of scaling and root planing for treatment of periodontitis. Materials & Methods: 20 patients with chronic moderate periodontitis and clinical attachment loss of at least 2mm and pocket depth of at least 3mm enrolled in this randomized double blind clinical trial. Scaling and root planning was done for all patients. Subgingival placement of chlorhexidine gel (Chlo-site) also was done in intervention group. Gingival Index (GI), pelaque Index (PI), pocket depth (PD) and clinical attachment loss (CAL) was measured before and 3 month after treatment. Data was evaluated by Mann-Whitney, Wilcoxon, Paired and independent sample t-test and ANOVA using SPSS software (α=0.05). Results: Before treatment, there statistically significant differences in parameters between the two groups. After treatment, the intervention group had were not significantly greater reduction in pocket depth and gingival index than the control group (α≤0.05) and improvement of clinical attachment level was significantly greater in the intervention group (α≤0.05). Conclusion: The findings suggest increased efficiency of the clinical treatment of chronic periodontitis with subgingival placement of chlorhexidine gel as adjunctive treatment.