[Lymph node metastasis regularity and risk factors in 768 cardiac carcinoma patients].

OBJECTIVE: To investigate the regularity of lymph node metastasis in cardiac carcinoma and its risk factors. METHOD: Complete clinicopathological data of 768 cardiac carcinoma patients undergoing radical resection and lymph node dissection were collected. A retrospective cohort study was performed to analyze the distribution of lymph node metastasis (lymph node metastasis rate=number of patients with lymph node metastasis/number of patients with lymph node dissection; lymph node metastasis frequency=number of metastatic lymph node/number of total resected lymph node) and the influence of clinicopathological factors on lymph node metastasis. RESULTS: =50.496, P=0.000). Multivariate analysis revealed that higher T stage (OR=2.326, 95%CI: 1.758 to 3.078, P=0.000) and resected lymph node number ≥12(OR=2.998, 95%CI: 2.142 to 4.195, P=0.000) were independent risk factors of lymph node metastasis. CONCLUSIONS: The lymph node metastasis rate of cardiac carcinoma is quite high. The metastasis occurs mainly in the surrounding of cardia, the small curvature of the stomach, the left artery of stomach and posterior pancreatic. The depth of tumor invasion and the number of lymph node dissection are independent risk factors of lymph node metastasis.