2019•Cleveland Clinic Journal of MedicineOpen access

Three neglected numbers in the CBC: The RDW, MPV, and NRBC count

Jori E. May, Marisa B. Marques, Vishnu Reddy, Radhika Gangaraju

Abstract

The complete blood cell count (CBC) is one of the most frequently ordered laboratory tests, but some values included in the test may be overlooked. This brief review discusses 3 potentially underutilized components of the CBC: the red blood cell distribution width (RDW), the mean platelet volume (MPV), and the nucleated red blood cell (NRBC) count. These results have unique diagnostic applications and prognostic implications that can be incorporated into clinical practice. By understanding all components of the CBC, providers can learn more about the patient's condition.

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Key concepts: Complete blood count, Medicine, Red blood cell distribution width, Blood count, Mean platelet volume, Nucleated Red Blood Cell, Internal medicine, Platelet