2018International Journal of Clinical Nutrition & DieteticsOpen access

Effects of Anti-oxidants on Oxidative Stress: Assessing MDA in Urine Samples

Sundardas Annamalay

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Abstract

This study looked at reducing oxidative stress and free radicals using oral antioxidants. Malondialdehyde (MDA) is widely used as a biomarker for assessing oxidative stress in biomedical fields and in many health problems such as cancer, psychiatry, chronic obstructive pulmonary disease, asthma, or cardiovascular diseases. Lipid peroxidation is a chain phenomenon resulting in the formation of various active compounds that result in cellular damage and another mechanism involved in oxidative stress. Oxidative stress status was determined using the urinary malondialdehyde test. Preliminary conclusion suggests that oxidative stress in the body can be reduced with appropriate oral anti-oxidants. However future research has to determine to what extent the digestive system and the stress hormonal systems can impact the oxidative status.

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This study looked at reducing oxidative stress and free radicals using oral antioxidants. Malondialdehyde (MDA) is widely used as a biomarker for assessing oxidative stress in biomedical fields and in many health problems such as cancer, psychiatry, chronic obstructive pulmonary disease, asthma, or cardiovascular diseases. Lipid peroxidation is a chain phenomenon resulting in the formation of various active compounds that result in cellular damage and another mechanism involved in oxidative stress. Oxidative stress status was determined using the urinary malondialdehyde test. Preliminary conclusion suggests that oxidative stress in the body can be reduced with appropriate oral anti-oxidants. However future research has to determine to what extent the digestive system and the stress hormonal systems can impact the oxidative status.

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Available abstract

This study looked at reducing oxidative stress and free radicals using oral antioxidants. Malondialdehyde (MDA) is widely used as a biomarker for assessing oxidative stress in biomedical fields and in many health problems such as cancer, psychiatry, chronic obstructive pulmonary disease, asthma, or cardiovascular diseases. Lipid peroxidation is a chain phenomenon resulting in the formation of various active compounds that result in cellular damage and another mechanism involved in oxidative stress. Oxidative stress status was determined using the urinary malondialdehyde test. Preliminary conclusion suggests that oxidative stress in the body can be reduced with appropriate oral anti-oxidants. However future research has to determine to what extent the digestive system and the stress hormonal systems can impact the oxidative status.

Key concepts: Malondialdehyde, Oxidative stress, Lipid peroxidation, Biomarker, Urine, Oxidative phosphorylation, Urinary system, Medicine

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