Outcome and risk factors of post-traumatic endophthalmitis over a 5-year period in North China

Background: To study the outcome and risk factors of post-traumatic endophthalmitis over a 5-year period in North China. Method: We reviewed the medial records of 66 consecutive patients presenting with post-traumatic endophthalmitis and having more than 6 months follow up. Results: During the last 5 years, we treated 66 post-traumatic endophthalmitis cases, representing 77.65% of all types of endophthalmitis. The infection rate in open globe injuries was 12.92% and 25.30%, if intraocular foreign body (IOFB) was associated. Culture was positive in 18 cases (27.3%). We administered antibiotic and anti-inflammatory drugs, systemically and intravitreally, in all cases. We performed pars plana vitrectomy (PPV) with silicone oil tamponade in 68.2% of cases. We also performed enucleation/evisceration in 22.7% of cases. In 36.4% of cases, the final visual acuity was 0.1 or more. Conclusions: Post-traumatic endophthalmitis are associated with significant visual impairment. IOBF significantly increased the risk for endophthalmitis. The most common time occurred endophthalmitis was 72 hours to 1 week after the primary injury. The factors associated a worse prognosis in post-traumatic endophthalmitis were retinal detachment (RD), delayed primary repair, poor initial best corrected visual acuity (BCVA) and fungal infection.