Assessment of Photodynamic Therapy and Miconazole in the Management of Denture Stomatitis

Objectives: Candida-induced denture stomatitis can be treated with different approaches; one of the most effective methods is the Photodynamic therapy (PDT). The current study aimed to assess the collective effects of PDT and low-level laser therapy (LLLT) in comparison to the topical application of miconazole gel. Materials and Methods: Thirty complete denture wearers with a history of Candida-induced denture stomatitis were haphazardly divided into two groups 15 patient each. Group I: The patients were subjected to a session of methylene blue-mediated PDT followed by to 2 sessions of (LLLT) 2 times per week for 15 days, while those of Group II: were subjected to miconazole gel four times per day for fifteen days. Results: The clinical and cytolological findings revealed that 50% of the patients in Group I have been cured from denture stomatitis while in Group II the curing rate was 85%. After two weeks following treatment stoppage, 30% of Group I patients showed reappearance of symptoms while the ration of recurrence was 15% in Group II patients. Conclusion: Photodynamic therapy associated with low level laser therapy (LLLT) and Miconazole gel can be considered effective methods in the management of Candida-induced denture stomatitis with higher curing rate and lower recurrence ratio for Miconazole.