2018•Unpublished venueRequires access
Analysis of integrated inflammatory bowel disease mouse models to assess their disease driving pathways and relevance for Crohn’s disease and Ulcerative colitis
Weiwei Schultz, Calixte S. Monast, Mathias Hesse, Leon Chang, Michael Scully, Yanqing Chen, Xuejun Liu, Zachary Hutchins, Stelios Pavlidis, Frédéric Baribaud
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Abstract
In this paper, we propose an analytic approach based on gene set variation analysis (GSVA) and network analysis to compare different mouse inflammatory bowel disease (IBD) models and assess their pertinence to Crohn's disease and ulcerative colitis.