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ChemInform Abstract: Trifluoroacetic Acid in 2,2,2‐Trifluoroethanol Facilitates SNAr Reactions of Heterocycles with Arylamines.

Bernard T. Golding, et al. et al.

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Abstract

Abstract Trifluoroacetic acid/2,2,2‐trifluoroethanol (TFA‐TFE) is used as an effective combination for achieving SNAr reactions between heterocycles (e.g., purines and pyrimidines) bearing a suitable leaving group and anilines.

About this research paper

What this paper is about

Abstract Trifluoroacetic acid/2,2,2‐trifluoroethanol (TFA‐TFE) is used as an effective combination for achieving SNAr reactions between heterocycles (e.g., purines and pyrimidines) bearing a suitable leaving group and anilines.

Why it matters

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Method / approach

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Available abstract

Abstract Trifluoroacetic acid/2,2,2‐trifluoroethanol (TFA‐TFE) is used as an effective combination for achieving SNAr reactions between heterocycles (e.g., purines and pyrimidines) bearing a suitable leaving group and anilines.

Key concepts: Chemistry, Trifluoroacetic acid, Organic chemistry, Medicinal chemistry, Trifluoroacetic anhydride, Combinatorial chemistry

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ChemInform Abstract: Trifluoroacetic Acid in 2,2,2‐Trifluoroethanol Facilitates SNAr Reactions of Heterocycles with Arylamines. — Research Paper | ScholarLens