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2019•Antimicrobial Agents and ChemotherapyOpen access

Detection of mcr -Mediated Colistin Resistance in Escherichia coli Isolates from Pigs in Small-Scale Farms in Cambodia

Gunilla Ström Hallenberg, Stefan Börjesson, S. Sokerya, T. Sothyra, Ulf Magnusson

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Abstract

Colistin is today considered a last-line antimicrobial for the treatment of infections in humans caused by multidrug-resistant Enterobacteriaceae [1]. The dissemination of colistin resistance has received increased attention since a mobilized gene conferring resistance to colistin, mcr-1 , was described in Enterobacteriaceae from humans and food-producing animals in China in 2015 [2], and additional gene homologs have since been identified [3-15].

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What this paper is about

Colistin is today considered a last-line antimicrobial for the treatment of infections in humans caused by multidrug-resistant Enterobacteriaceae [1]. The dissemination of colistin resistance has received increased attention since a mobilized gene conferring resistance to colistin, mcr-1 , was described in Enterobacteriaceae from humans and food-producing animals in China in 2015 [2], and additional gene homologs have since been identified [3-15].

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Available abstract

Colistin is today considered a last-line antimicrobial for the treatment of infections in humans caused by multidrug-resistant Enterobacteriaceae [1]. The dissemination of colistin resistance has received increased attention since a mobilized gene conferring resistance to colistin, mcr-1 , was described in Enterobacteriaceae from humans and food-producing animals in China in 2015 [2], and additional gene homologs have since been identified [3-15].

Key concepts: Colistin, MCR-1, Enterobacteriaceae, Microbiology, Biology, Escherichia coli, Multiple drug resistance, Enterobacteriaceae Infections

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Detection of mcr -Mediated Colistin Resistance in Escherichia coli Isolates from Pigs in Small-Scale Farms in Cambodia — Research Paper | ScholarLens