2018•International Research Journal of PharmacyOpen access

ULTRASOUND PROMOTED ONE POT SYNTHESIS OF 1,5-BENZOTHIAZEPINES USING POLYETHYLENE GLYCOL (PEG-400)

Chandrashekhar G Devkate, S. Kola, Digambar D. Gaikwad, Mohammad Idrees M Siddique

Abstract

Synthesis of a variety of 1,5-benzothiazepines using polyethylene glycol PEG-400 as a medium and promoter.The synthesis is carried out using ultrasonic irradiation.The advantage of this protocol is that it eco-friendly, mild reaction conditions and the synthesis highlights the use of ultrasound irradiation.

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Key concepts: Polyethylene glycol, PEG ratio, Ultrasound, Chemistry, Nuclear chemistry, Medicine, Organic chemistry, Business