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2018•Catheterization and Cardiovascular InterventionsRequires access

Embolic stroke of undetermined source and patent foramen ovale closure: Practice insights from meta‐analysis?

Arka Chatterjee, William B. Hillegass

Open publisher page 2 citations

Abstract

Closure of patent foramen ovale (PFO) in embolic stroke of undetermined source (ESUS) reduces recurrent stroke compared with antiplatelet therapy in select patients but increases risk of atrial fibrillation. Device closure is an attractive option for young patients with an anatomically higher risk PFO and imaging proven ESUS. Benefit of PFO closure in ESUS compared with oral anticoagulation remains undefined.

About this research paper

What this paper is about

Closure of patent foramen ovale (PFO) in embolic stroke of undetermined source (ESUS) reduces recurrent stroke compared with antiplatelet therapy in select patients but increases risk of atrial fibrillation. Device closure is an attractive option for young patients with an anatomically higher risk PFO and imaging proven ESUS. Benefit of PFO closure in ESUS compared with oral anticoagulation remains undefined.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Closure of patent foramen ovale (PFO) in embolic stroke of undetermined source (ESUS) reduces recurrent stroke compared with antiplatelet therapy in select patients but increases risk of atrial fibrillation. Device closure is an attractive option for young patients with an anatomically higher risk PFO and imaging proven ESUS. Benefit of PFO closure in ESUS compared with oral anticoagulation remains undefined.

Key concepts: Medicine, Patent foramen ovale, Embolic stroke, Stroke (engine), Atrial fibrillation, Closure (psychology), Cardiology, Internal medicine

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Embolic stroke of undetermined source and patent foramen ovale closure: Practice insights from meta‐analysis? — Research Paper | ScholarLens