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2018•VaccineOpen access

Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro

Anne Marie Queenan, David J. Dowling, Wing Ki Cheng, Kellen C. Faé, Jeffrey Fernandez, Peter J. Flynn, Sweta Joshi, Spencer E. Brightman, Juan Camilo Ramírez, Jan Serroyen, Selma P. Wiertsema, Alexandre C. Fortanier, Germie van den Dobbelsteen, Ofer Levy, Jan Poolman

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Key concepts: Reactogenicity, Pertactin, Bordetella pertussis, Pertussis vaccine, Vaccine efficacy, Pertussis toxin, Medicine, Microbiology

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Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro — Research Paper | ScholarLens