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2018•GSC Biological and Pharmaceutical SciencesOpen access

Anti-inflammatory activity Keelvayu nivarana churnam in carrageenan induced inflammatory rats

V. Elango, G. Vijayabaskar

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Abstract

Anti-inflammatory activity of Keelvayu nivarana churnam in carrageenan induced inflammatory rats was evaluated. Keelvayu nivarana churnam at the doses of 10, 15 mg/kg and 25 mg/kg of body weight in experimental animals. Anti-inflammatory activity was evaluated by Carrageenan induced paw edema in rats. Indomethacin (3 mg/Kg body weight) was employed as standard drug. Animals were randomized into 4 group (n = 6). Control group receives vehicle only. Keelvayu nivarana churnam treated with high dose which produced significant inhibition of edema and pain. This study confirms Keelvayu nivarana churnam possesses significant anti-inflammatory efficacy.

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Anti-inflammatory activity of Keelvayu nivarana churnam in carrageenan induced inflammatory rats was evaluated. Keelvayu nivarana churnam at the doses of 10, 15 mg/kg and 25 mg/kg of body weight in experimental animals. Anti-inflammatory activity was evaluated by Carrageenan induced paw edema in rats. Indomethacin (3 mg/Kg body weight) was employed as standard drug. Animals were randomized into 4 group (n = 6). Control group receives vehicle only. Keelvayu nivarana churnam treated with high dose which produced significant inhibition of edema and pain. This study confirms Keelvayu nivarana churnam possesses significant anti-inflammatory efficacy.

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Available abstract

Anti-inflammatory activity of Keelvayu nivarana churnam in carrageenan induced inflammatory rats was evaluated. Keelvayu nivarana churnam at the doses of 10, 15 mg/kg and 25 mg/kg of body weight in experimental animals. Anti-inflammatory activity was evaluated by Carrageenan induced paw edema in rats. Indomethacin (3 mg/Kg body weight) was employed as standard drug. Animals were randomized into 4 group (n = 6). Control group receives vehicle only. Keelvayu nivarana churnam treated with high dose which produced significant inhibition of edema and pain. This study confirms Keelvayu nivarana churnam possesses significant anti-inflammatory efficacy.

Key concepts: Carrageenan, Edema, Anti-inflammatory, Body weight, Pharmacology, Inflammation, Positive control, Medicine

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