2018Journal of Pharmacology and PharmacotherapeuticsOpen access

Need of the Hour: Warfarin-induced Massive Intraperitoneal Bleed

Vinayaka Anuhya, Sharath P Madhyastha, Veena Nayak, Gangaparameswari Soundarrajan, Raviraj Acharya

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Abstract

Warfarin is an oral anticoagulant which is a natural coumarin derivative used for the treatment of various diseases such as thromboembolic disorders, prosthetic heart valves, and atrial fibrillation. Bleeding tendencies have been the most commonly reported adverse effects of warfarin, limiting its use and requiring the need for regular monitoring. Despite many warfarin management strategies being taken for the prevention, bleeding still continues to be a problem to be dealt with. The authors report a case of spontaneous intraperitoneal bleeding due to warfarin use in a 54-year-old female patient.

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What this paper is about

Warfarin is an oral anticoagulant which is a natural coumarin derivative used for the treatment of various diseases such as thromboembolic disorders, prosthetic heart valves, and atrial fibrillation. Bleeding tendencies have been the most commonly reported adverse effects of warfarin, limiting its use and requiring the need for regular monitoring. Despite many warfarin management strategies being taken for the prevention, bleeding still continues to be a problem to be dealt with. The authors report a case of spontaneous intraperitoneal bleeding due to warfarin use in a 54-year-old female patient.

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Available abstract

Warfarin is an oral anticoagulant which is a natural coumarin derivative used for the treatment of various diseases such as thromboembolic disorders, prosthetic heart valves, and atrial fibrillation. Bleeding tendencies have been the most commonly reported adverse effects of warfarin, limiting its use and requiring the need for regular monitoring. Despite many warfarin management strategies being taken for the prevention, bleeding still continues to be a problem to be dealt with. The authors report a case of spontaneous intraperitoneal bleeding due to warfarin use in a 54-year-old female patient.

Key concepts: Warfarin, Bleed, Medicine, Atrial fibrillation, Anticoagulant, Major bleeding, Coumarin, Limiting

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