2011•FigshareOpen access
Contribution of tumor necrosis factor (TNF) to lipopolysaccharide (LPS) induction of tristetraprolin (TTP) in THP-1 cells
Anna‐Marie Fairhurst, John Edward Connolly, Katharine A Hintz, Nicolas J. Goulding, Athos J. Rassias, Mark P. Yeager, William F. C. Rigby, Paul K. Wallace
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Abstract
Copyright information:Taken from "Regulation and localization of endogenous human tristetraprolin"Arthritis Research & Therapy 2003;5(4):R214-R225.Published online 15 May 2003PMCID:PMC165067.Copyright © 2003 Fairhurst et al., licensee BioMed Central Ltd The cells were incubated with LPS or TNF in the absence or presence of blocking TNF antibody (infliximab [Remicade]), and TTP levels were measured at specific times. Results are expressed as percentage change from baseline expression (mean ± SE). Experiments were performed in duplicate.