Secukinumab for plaque psoriasis with ocular comorbidity: a clinical experience
Serafinella Patrizia Cannavò, Elisa Imelde Postorino, Emanuela Aragona, Annunziata Bartolotta, Valeria Papaianni, Claudio Guarneri
Abstract
Serafinella Patrizia Cannavò, Elisa Imelde Postorino, Emanuela Aragona, Annunziata Bartolotta, Valeria Papaianni, Claudio Guarneri
Abstract
Psoriasis is a systemic inflammatory disorder associated with many other chronic and progressive diseases. Ocular comorbidity has been reported in 10-15% of patients with plaque psoriasis, but the real incidence is still underestimated. This paper reports successful treatment with secukinumab of a patient with plaque psoriasis and dry eye syndrome. Secukinumab treatment was rapidly effective on skin psoriasis and this result was in agreement with observations reported in the literature. Interestingly, both the skin condition and the ocular disease improved after treatment. Our experience suggests that this drug should be used in patients with plaque psoriasis and ophthalmologic manifestations.
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Psoriasis is a systemic inflammatory disorder associated with many other chronic and progressive diseases. Ocular comorbidity has been reported in 10-15% of patients with plaque psoriasis, but the real incidence is still underestimated. This paper reports successful treatment with secukinumab of a patient with plaque psoriasis and dry eye syndrome. Secukinumab treatment was rapidly effective on skin psoriasis and this result was in agreement with observations reported in the literature. Interestingly, both the skin condition and the ocular disease improved after treatment. Our experience suggests that this drug should be used in patients with plaque psoriasis and ophthalmologic manifestations.
Key concepts: Secukinumab, Medicine, Dermatology, Comorbidity, Psoriasis, Plaque psoriasis, Psoriatic arthritis, Internal medicine