2018•Organic & Biomolecular ChemistryRequires access
An alternative route for the synthesis of hydroxylated pillar[5]arene-based amphiphiles
Talal F. Al‐Azemi, Mickey Vinodh, Fatemeh H. Alipour, Abdirahman A. Mohamod
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Abstract
Conformational mobilities of the units and host-guest complexation with n-octyltrimethylammonium hexafluorophosphate of the synthesized perbenzylated pillar[5]arenes were studied. The formed complex was confirmed by proton nuclear magnetic resonance spectroscopy and mass spectral analysis. Hydroxylated pillar[5]arene-based amphiphiles were synthesized by a co-cyclization strategy followed by catalytic hydrogenation. This approach unlocks the synthesis and the design of a wide range of structural manipulations to these amphiphilic pillararenes.