2018•Journal of Materials Chemistry BRequires access

Phthalocyanine-based photosensitizer with tumor-pH-responsive properties for cancer theranostics

Shufeng Yan, Jincan Chen, Liangzhi Cai, Peng Xu, Yaxin Zhang, Shijie Li, Ping Hu, Xueyuan Chen, Mingdong Huang, Zhuo Chen

Open publisher page 33 citations

Abstract

not only ablated tumor cells photodynamically but also presented clear fluorescence cell imaging of tumor sites. These findings suggest that such a tumor-pH-responsive photosensitizer based on phthalocyanine may open up a new avenue for tumor-targeted and image-guided cancer theranostics in PDT.

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Key concepts: Photosensitizer, Phthalocyanine, Photodynamic therapy, Materials science, Photochemistry, Nanotechnology, Chemistry, Organic chemistry