ScholarLens Back to search
2018•Obstetric Anesthesia DigestRequires access

Effects of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-ischemic Encephalopathy

Abbot R. Laptook, Seetha Shankaran, Jon E. Tyson, Byron Rolando Chango Muñoz, Edward F. Bell, Ron N. Goldberg, Nehal A. Parikh, Namasivayam Ambalavanan, Claudia Pedroza, Athina Pappas, Abhik Das, Aasma S. Chaudhary, Richard A. Ehrenkranz, Angelita M. Hensman, Krisa P. Van Meurs, Lina F. Chalak, Shannon E. G. Hamrick, Gregory M. Sokol, Michelle Walsh, Brenda B. Poindexter, R G Faix, Kristi L. Watterberg, Ivan D. Frantz, Ronnie Guillet, Uday Devaskar, William E. Truog, Valerie Y. Chock, Myra H. Wyckoff, Elisabeth C. McGowan, D P Carlton, Heidi M. Harmon, Jane E. Brumbaugh, C. Michael Cotten, Pablo J. Sánchez, Anna Maria Hibbs, Rosemary D. Higgins

Open publisher page 9 citations

Abstract

( JAMA 2017;318(16):1550–1560) Previous trials have shown therapeutic hypothermia reduces death or disability when infants with hypoxic-ischemic encephalopathy are treated within 6 hours after birth. Getting infants treated in this window can be difficult when transportation is necessary or when encephalopathy is not recognized within 6 hours. This study aimed to determine whether hypothermia treatment can reduce the risk of death or disability due to hypoxic-ischemic encephalopathy at 18 months when treatment is initiated between 6 and 24 hours after birth.

About this research paper

What this paper is about

( JAMA 2017;318(16):1550–1560) Previous trials have shown therapeutic hypothermia reduces death or disability when infants with hypoxic-ischemic encephalopathy are treated within 6 hours after birth. Getting infants treated in this window can be difficult when transportation is necessary or when encephalopathy is not recognized within 6 hours. This study aimed to determine whether hypothermia treatment can reduce the risk of death or disability due to hypoxic-ischemic encephalopathy at 18 months when treatment is initiated between 6 and 24 hours after birth.

Why it matters

OpenAlex reports 9 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

( JAMA 2017;318(16):1550–1560) Previous trials have shown therapeutic hypothermia reduces death or disability when infants with hypoxic-ischemic encephalopathy are treated within 6 hours after birth. Getting infants treated in this window can be difficult when transportation is necessary or when encephalopathy is not recognized within 6 hours. This study aimed to determine whether hypothermia treatment can reduce the risk of death or disability due to hypoxic-ischemic encephalopathy at 18 months when treatment is initiated between 6 and 24 hours after birth.

Key concepts: Medicine, Hypothermia, Hypoxic Ischemic Encephalopathy, Encephalopathy, Anesthesia, Neonatal encephalopathy, Hypoxia (environmental), Pediatrics

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Effects of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-ischemic Encephalopathy — Research Paper | ScholarLens