2018•Chemico-Biological InteractionsRequires access

The enhancement of cardiotoxicity that results from inhibiton of CYP 3A4 activity and hERG channel by berberine in combination with statins

Panfeng Feng, Lei Zhao, Feng-Feng Guo, Bo Zhang, Fang Li, Ge Zhan, Xueqi Xu, Qing Ze Fang, Zhaoguang Liang, Baoxin Li

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Key concepts: hERG, Pharmacology, Berberine, Cardiotoxicity, CYP3A4, Atorvastatin, Chemistry, Simvastatin

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The enhancement of cardiotoxicity that results from inhibiton of CYP 3A4 activity and hERG channel by berberine in combination with statins — Research Paper | ScholarLens