2018•Bioorganic & Medicinal ChemistryOpen access

In vitro and in vivo pharmacokinetic and pharmacodynamic study of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent

Mingxu Ma, Jianchun Zhao, Hejuan Cheng, Mengyan Deng, Zhongpeng Ding, Yingwei Hou, Feng Li, Guifang Dou, Wenbao Li

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Key concepts: In vivo, Pharmacokinetics, Pharmacology, Chemistry, In vitro, Pharmacodynamics, Microsome, Biochemistry

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In vitro and in vivo pharmacokinetic and pharmacodynamic study of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent — Research Paper | ScholarLens