Effects of Glycemic Index and Intake of Dietary Fiber on Serum HDL-Cholesterol Levels

We previously studied effects of glycemic index (GI) and intake of dietary fiber on serum high-density lipoprotein (HDL)-C levels to make “Dietary Reference Intakes for Japanese 2015”, by using data obtained by clinical trials which evaluated effects of GI and intake of dietary fiber on HDL-C in Asian populations. We found that low GI and an increased intake of dietary fiber may be beneficially associated with HDL metabolism. Here we review meta-analyses on the effects of GI and intake of dietary fiber on serum HDL-C levels, to make “Dietary Reference Intake for Japanese 2020”. A search was conducted by using PubMed, Embase and Google Scholar, and the search period was comprised up to May 2018. In spite of significant associations of low GI and dietary fiber intake with reduction of low-density lipoprotein (LDL)-C, we could not observe any significant influences of low GI and dietary fiber intake on HDL metabolism. J Endocrinol Metab. 2018;8(4):57-61 doi: https://doi.org/10.14740/jem514w