2016•CirculationRequires access

Abstract 17405: Small K+ Channel Activity Modulates Sinoatrial Node Pacemaker Rate and Explains the Abnormal Bursts of Sinoatrial Node Pacing in Atrial-Specific Na+/Ca2+ Exchange Knockout Mice

Angelo G. Torrente, Rui Zhang, Heidy Wang, Audrey Zaini, Brian Y. Kim, Kenneth D. Philipson, Joshua I. Goldhaber

Abstract

Rationale: Ca2+-sensitive small K+ (SK) channels have been implicated in abnormal atrial repolarization, automaticity and conduction in the heart. Despite their potential role in sinoatrial node (S...

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Sinoatrial node, Medicine, Cardiology, Internal medicine, Heart rate, Node (physics), Knockout mouse, Artificial cardiac pacemaker