Studies on Pathology and Therapeutic Efficacy of Anthiomaline in Bovine Papillomatosis

Bovine papillomatosis is a viral disease of cattle characterized clinically by development of multiple benign tumours termed warts. The diagnosis of bovine papillomatosis was confirmed by clinical and pathological examinations of the warts. The aim of the present investigation was to study the pathology of papillomas and to evaluate the therapeutic efficacy of anthiomaline in bovine papillomatosis. Six buffaloes suspected with papillomatosis were treated with anthiomaline (lithium antimony thiomalate) at the dose rate of 15 ml deep intramuscularly on alternate days in adult animals and 7 ml deep intramuscularly on alternate days in young ones i.e. calves. Gross and histopathological examination of the tumour masses revealed five cases of papilloma characterised by similar lesions of orthokeratotic hyperkeratosis, finger-like papillae with numerous vacuolating cells with eccentrically placed nuclei and one of leiomyoma. Anthiomaline was found to be effective in all the cases as no recurrence was observed in follow up study period of one year. It may be concluded that anthiomaline can be effectively used for treating cases of papilloma in bovines.