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Determination of adenosine and cordycepin in Cordyceps products by Ultrahigh-Performance Liquid Chromatography.

Lei Ping, Huang ZhiYing, Lin Miao, Yang HaiHua, Yuting Chen

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Abstract

Adenosine and cordycepin levels in twelve Cordyceps products were successfully determined by Ultrahigh-Performance Liquid Chromatography(UPLC) using an ACQUITY C18 column,with water and acetonitrile as the mobile phase.Separation of the two components was achieved within four minutes,and the concentrations of each component showed a linear relationship with the peak area in the range 2～20 μg/mL.Detection limits(S/N=3) were 0.10 μg/mL and 0.12 μg/mL for adenosine and cordycepin,respectively.

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What this paper is about

Adenosine and cordycepin levels in twelve Cordyceps products were successfully determined by Ultrahigh-Performance Liquid Chromatography(UPLC) using an ACQUITY C18 column,with water and acetonitrile as the mobile phase.Separation of the two components was achieved within four minutes,and the concentrations of each component showed a linear relationship with the peak area in the range 2～20 μg/mL.Detection limits(S/N=3) were 0.10 μg/mL and 0.12 μg/mL for adenosine and cordycepin,respectively.

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Available abstract

Adenosine and cordycepin levels in twelve Cordyceps products were successfully determined by Ultrahigh-Performance Liquid Chromatography(UPLC) using an ACQUITY C18 column,with water and acetonitrile as the mobile phase.Separation of the two components was achieved within four minutes,and the concentrations of each component showed a linear relationship with the peak area in the range 2～20 μg/mL.Detection limits(S/N=3) were 0.10 μg/mL and 0.12 μg/mL for adenosine and cordycepin,respectively.

Key concepts: Cordycepin, Cordyceps, High-performance liquid chromatography, Adenosine, Chromatography, Chemistry, Linear range, Detection limit

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Determination of adenosine and cordycepin in Cordyceps products by Ultrahigh-Performance Liquid Chromatography. — Research Paper | ScholarLens