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2018•Internal MedicineOpen access

Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems

Taku Sugawa, Takaaki Murakami, Daisuke Yabe, Riko Kashima, Makiko Tatsumi, Shinobu Ooshima, Erina Joo, Keiko Wada, Atsushi Yoshizawa, Toshihiko Masui, Yuji Nakamoto, Yuki Yamauchi, Yuzo Kodama, Yoshiki Iemura, Masahito Ogura, Akihiro Yasoda, Nobuya Inagaki

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Abstract

The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.

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What this paper is about

The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.

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OpenAlex reports 19 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.

Key concepts: Insulinoma, Hypoglycemia, Medicine, Postprandial, Continuous glucose monitoring, Internal medicine, Blood Glucose Self-Monitoring, Insulin

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