Comparison of Esmolol bolus with Esmolol infusion in reducing peri-intubation stress response in non cardiac surgical patients: A randomized controlled trial
Toms Ann Sumin
Abstract
Toms Ann Sumin
Abstract
To compare the effects of esmolol bolus versus esmolol infusion in reducing the stress response to intubation. 2. To identify which mode of Esmolol administration (infusion/ bolus) reduces the stress response effectively with the least side effects in patients undergoing non cardiac surgery. The rise in blood pressure following intubation was ablated by both esmolol bolus and infusion, but both bolus and infusion failed to effectively prevent the heart rate response to intubation. Esmolol infusion has better haemodynamic stability than esmolol bolus.
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To compare the effects of esmolol bolus versus esmolol infusion in reducing the stress response to intubation. 2. To identify which mode of Esmolol administration (infusion/ bolus) reduces the stress response effectively with the least side effects in patients undergoing non cardiac surgery. The rise in blood pressure following intubation was ablated by both esmolol bolus and infusion, but both bolus and infusion failed to effectively prevent the heart rate response to intubation. Esmolol infusion has better haemodynamic stability than esmolol bolus.
Key concepts: Esmolol, Bolus (digestion), Anesthesia, Medicine, Intubation, Hemodynamics, Heart rate, Blood pressure