Association of Hypothyroidism in Obstructive Sleep Apnea Syndrome

Background: Hypothyroidism and obstructive sleep apnea syndrome (OSAS) are common comorbid conditions with overlapping clinical presentation.We decided to study the association of hypothyroidism in our OSAS patients.Methodology: This observational study included 108 patients with clinical features suggesting OSAS.The clinical details were noted; Polysomnography (PSG) and thyroid function tests (TFT) were done.Qualitative and quantitative data was analyzed with appropriate tests.Results: Seventy-two (66.7%) men and 36 (33.3%) women were included.PSG confirmed OSAS in 78 (72.2%).The severity of OSAS was mild, moderate, severe in 30 (38%), 28 (36%), 20 (26%) respectively.Thirteen (12%) had hypothyroidism; subclinical in 2 (15%) and clinical in 11 (85%).Only 2 (15%) were on optimal medical treatment.Hypothyroidism was seen in 11(14%) of OSAS, against in 2(7%) of the non-OSAS group.OSAS was found in 11(85%) of hypothyroid, against in 67 (71%) of the Euthyroid group.A statistically significant association between OSAS and hypothyroidism treatment was observed.Conclusion: The prevalence of hypothyroidism was higher in OSAS; though statistically insignificant.Association between OSAS and hypothyroidism treatment was statistically significant.