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2018•Journal of Asthma and AllergyOpen access

Underuse of epinephrine for the treatment of anaphylaxis: missed opportunities

Benjamin T. Prince, Irene Mikhail, David R. Stukus

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Abstract

Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has been associated with delayed administration of epinephrine. Many potential barriers exist to the proper use of epinephrine during an anaphylactic reaction. This article will explore both patient-and physician-related factors, as well as misconceptions that all contribute to the underuse of epinephrine for the treatment of anaphylaxis.

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What this paper is about

Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has been associated with delayed administration of epinephrine. Many potential barriers exist to the proper use of epinephrine during an anaphylactic reaction. This article will explore both patient-and physician-related factors, as well as misconceptions that all contribute to the underuse of epinephrine for the treatment of anaphylaxis.

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OpenAlex reports 125 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has been associated with delayed administration of epinephrine. Many potential barriers exist to the proper use of epinephrine during an anaphylactic reaction. This article will explore both patient-and physician-related factors, as well as misconceptions that all contribute to the underuse of epinephrine for the treatment of anaphylaxis.

Key concepts: Anaphylaxis, Epinephrine, Medicine, Anesthesia, Intensive care medicine, Anaphylactic reactions, Allergy, Immunology

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