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The immune response of swine to transmissible gastroenteritis virus

Linda J. Saif

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Abstract

a titu d e i s ex p ressed to t h e many p eople whose c o o p eratio n and a s s is ta n c e were im p o rtan t i n p u rsu in g t h i s g rad u a te program . 1 am in d e b te d to D r. E. H. B ohl, my a d v is e r, f o r h i s tim e, ad v ice and encouragem ent in t h i s p r o je c t.The su p p o rt and i n t e r e s t o f D r. L, C, Ferguson a re g r a t e f u l l y acknowledged.A p p re c ia tio n i s a ls o ex p re ssed t o Dr. B. S .Z w illin g , my c o -a d v is o r, and D r. D. A. W olff, f o r t h e i r guidance d u rin g my g ra d u a te program and h e lp f u l su g g e stio n s i n th e p re p a ra tio n o f t h i s d i s s e r t a t i o n .I am g r a t e f u l to a number o f people f o r t h e i r e x c e lle n t te c h n ic a l a s s i s t a n c e .My th a n k s to Ms. K athy M ille r f o r h e r h elp w ith th e v ir u s n e u tr a li z a t io n t e s t s .A lso , th e capable a s s i s t a n c e o f Ms. B arbara D a ft and Mr. Arden Agness in th e flu o r e s c e n t a n tib o d y s tu d ie s i s s i n c e r e ly a p p re c ia te d .The e x c e ll e n t photography o f » Hr* Glenn B erkey i s g r a t e f u l l y acknowledged.Many o f th e anim als and m a te ria ls u se d i n t h i s stu d y , a s w e ll a s p a r t o f th e f i n a n c ia l a s s is ta n c e were fun d ed through an A g r ic u ltu r a l R esearch S e rv ic e C ooperative Agreement No. 12-14-3001-2791 and a N a tio n a l I n s t i t u t e s o f H e alth (P u b lic H e a lth S e rv ic e ) G ran t No. AI10735, The s u p p o rt o f th e V e te rin a ry S c ie n c e D epartm ent, OARDC i s a ls o g r e a tly a p p re c ia te d .

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a titu d e i s ex p ressed to t h e many p eople whose c o o p eratio n and a s s is ta n c e were im p o rtan t i n p u rsu in g t h i s g rad u a te program . 1 am in d e b te d to D r. E. H. B ohl, my a d v is e r, f o r h i s tim e, ad v ice and encouragem ent in t h i s p r o je c t.The su p p o rt and i n t e r e s t o f D r. L, C, Ferguson a re g r a t e f u l l y acknowledged.A p p re c ia tio n i s a ls o ex p re ssed t o Dr. B. S .Z w illin g , my c o -a d v is o r, and D r. D. A. W olff, f o r t h e i r guidance d u rin g my g ra d u a te program and h e lp f u l su g g e stio n s i n th e p re p a ra tio n o f t h i s d i s s e r t a t i o n .I am g r a t e f u l to a number o f people f o r t h e i r e x c e lle n t te c h n ic a l a s s i s t a n c e .My th a n k s to Ms. K athy M ille r f o r h e r h elp w ith th e v ir u s n e u tr a li z a t io n t e s t s .A lso , th e capable a s s i s t a n c e o f Ms. B arbara D a ft and Mr. Arden Agness in th e flu o r e s c e n t a n tib o d y s tu d ie s i s s i n c e r e ly a p p re c ia te d .The e x c e ll e n t photography o f » Hr* Glenn B erkey i s g r a t e f u l l y acknowledged.Many o f th e anim als and m a te ria ls u se d i n t h i s stu d y , a s w e ll a s p a r t o f th e f i n a n c ia l a s s is ta n c e were fun d ed through an A g r ic u ltu r a l R esearch S e rv ic e C ooperative Agreement No. 12-14-3001-2791 and a N a tio n a l I n s t i t u t e s o f H e alth (P u b lic H e a lth S e rv ic e ) G ran t No. AI10735, The s u p p o rt o f th e V e te rin a ry S c ie n c e D epartm ent, OARDC i s a ls o g r e a tly a p p re c ia te d .

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a titu d e i s ex p ressed to t h e many p eople whose c o o p eratio n and a s s is ta n c e were im p o rtan t i n p u rsu in g t h i s g rad u a te program . 1 am in d e b te d to D r. E. H. B ohl, my a d v is e r, f o r h i s tim e, ad v ice and encouragem ent in t h i s p r o je c t.The su p p o rt and i n t e r e s t o f D r. L, C, Ferguson a re g r a t e f u l l y acknowledged.A p p re c ia tio n i s a ls o ex p re ssed t o Dr. B. S .Z w illin g , my c o -a d v is o r, and D r. D. A. W olff, f o r t h e i r guidance d u rin g my g ra d u a te program and h e lp f u l su g g e stio n s i n th e p re p a ra tio n o f t h i s d i s s e r t a t i o n .I am g r a t e f u l to a number o f people f o r t h e i r e x c e lle n t te c h n ic a l a s s i s t a n c e .My th a n k s to Ms. K athy M ille r f o r h e r h elp w ith th e v ir u s n e u tr a li z a t io n t e s t s .A lso , th e capable a s s i s t a n c e o f Ms. B arbara D a ft and Mr. Arden Agness in th e flu o r e s c e n t a n tib o d y s tu d ie s i s s i n c e r e ly a p p re c ia te d .The e x c e ll e n t photography o f » Hr* Glenn B erkey i s g r a t e f u l l y acknowledged.Many o f th e anim als and m a te ria ls u se d i n t h i s stu d y , a s w e ll a s p a r t o f th e f i n a n c ia l a s s is ta n c e were fun d ed through an A g r ic u ltu r a l R esearch S e rv ic e C ooperative Agreement No. 12-14-3001-2791 and a N a tio n a l I n s t i t u t e s o f H e alth (P u b lic H e a lth S e rv ic e ) G ran t No. AI10735, The s u p p o rt o f th e V e te rin a ry S c ie n c e D epartm ent, OARDC i s a ls o g r e a tly a p p re c ia te d .

Key concepts: Virology, Immune system, Virus, Biology, Immunology

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