2018•Journal of Clinical MicrobiologyOpen access

Performance of Chlamydia trachomatis OmcB Enzyme-Linked Immunosorbent Assay in Serodiagnosis of Chlamydia trachomatis Infection in Women

Kanupriya Gupta, LaDraka’ T. Brown, Rakesh K. Bakshi, Christen G. Press, Xiaofei Chi, Rachel Gorwitz, John R. Papp, William M. Geisler

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Abstract

Chlamydia trachomatis serological assays with improved sensitivity over commercially available assays are needed to evaluate the burden of C. trachomatis infection and the effectiveness of prevention efforts. We evaluated the performance of a C. trachomatis outer membrane complex protein B (OmcB) enzyme-linked immunosorbent assay (ELISA) in the detection of anti- C. trachomatis antibody responses in C. trachomatis -infected women.

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Key concepts: Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Chlamydia trachomatis infection, Virology, Microbiology, Serology, Biology