Jun‐Rong Song, Junjie Lan, Chao Chen, Shengcao Hu, Jialei Song, Wulin Liu, Xueyi Zeng, Hua‐Yong Lou, Yaacov Ben‐David, Weidong Pan
Abstract
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Twenty-four 14-sulfonamide–tetrandrine derivatives were synthesized. Compound 23 exhibited growth inhibition of MDA-MB-231 cells with an IC 50 value of 1.18 ± 0.14 μM.
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Twenty-four 14-sulfonamide–tetrandrine derivatives were synthesized. Compound 23 exhibited growth inhibition of MDA-MB-231 cells with an IC 50 value of 1.18 ± 0.14 μM.
Key concepts: Tetrandrine, Combinatorial chemistry, Chemistry, Pharmacology, Cancer, Stereochemistry, Nanotechnology, Medicine