2018•NeurologyRequires access

Author response: Wrist sensor reveals sympathetic hyperactivity and hypoventilation before probable SUDEP

Rosalind W. Picard, Matteo Migliorini, Chiara Caborni, Francesco Onorati, Giulia Regalia, Daniel Friedman, Orrin Devinsky

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Abstract

We appreciate the comments from Dr. Stewart on our article,1 and agree that obstructive apnea and laryngospasm are potentially relevant factors in some sudden unexpected death in epilepsy (SUDEP) cases. We also agree that laryngospasm can occur during seizures. Well-documented cases have been rarely reported in witnessed SUDEPs.

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Key concepts: Laryngospasm, Hypoventilation, Medicine, Epilepsy, Apnea, Anesthesia, Psychiatry, Respiratory system