Biased Agonism/Antagonism of Cardiovascular GPCRs for Heart Failure Therapy
Victoria L. Desimine, Katie A. McCrink, Barbara M Parker, Shelby L. Wertz, Jennifer Maning, Anastasios Lymperopoulos
Abstract
Victoria L. Desimine, Katie A. McCrink, Barbara M Parker, Shelby L. Wertz, Jennifer Maning, Anastasios Lymperopoulos
Abstract
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Key concepts: G protein-coupled receptor, Functional selectivity, Heterotrimeric G protein, Agonism, Biology, Arrestin, G protein-coupled receptor kinase, G protein