Structural Aspects of Ribosomal RNA Recognition by Ribosomal Proteins
А.Д. Никулин
Abstract
А.Д. Никулин
Abstract
This review is focused on the structural aspects of interaction between ribosomal proteins and ribosomal RNA in bacterial ribosomes and complexes of ribosomal proteins with specific fragments of ribosomal RNA. Special attention is given to the recognition of specific spatial architecture of the double-stranded ribosomal RNA by ribosomal proteins and to the role of unstructured protein regions in stabilization of distant ribosomal RNA segments.
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This review is focused on the structural aspects of interaction between ribosomal proteins and ribosomal RNA in bacterial ribosomes and complexes of ribosomal proteins with specific fragments of ribosomal RNA. Special attention is given to the recognition of specific spatial architecture of the double-stranded ribosomal RNA by ribosomal proteins and to the role of unstructured protein regions in stabilization of distant ribosomal RNA segments.
Key concepts: Ribosomal RNA, Ribosomal protein, Computational biology, 28S ribosomal RNA, 5.8S ribosomal RNA, 18S ribosomal RNA, 30S, 5S ribosomal RNA