2018Journal of Medical Science And clinical ResearchOpen access

Domicilliary use of Oral Mifepristone and Misoprostol in First trimester Medical Abortion

Dr S .V. Nachiketha

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Abstract

Objective: To evaluate medical abortion by Domicilliary administration of mifepristone and Misoprostol by assessing efficacy and women's acceptability.Methods: This was a retrospective study of 80 patients done from Jan 2017 to Jan 2018.Women with amenorrhoea of less than or equal to 63 days are advised to self administer 200 mg Mifepristone orally at home on day1.48 hrs later, oral 800 µg Misoprostol .All women followed up on day 14 of tab.Mifepristone for abortion confirmed by usg.Results: Efficacy of regimen was 100% in gestational age up to 49 days and 95.45 % in gestational age of 50-63 days.The overall success rate was 97.5%.most of the women were ready to choose same method in future if required.Conclusion: Medical abortion was simplified by Domicile use of oral mifepristone and Misoprostol as it required less hospital visits and less supervision by trained persons.Acceptability of home selfadministration was high.Hence home administration is safe and feasible for introduction into medical abortion services in India.

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Objective: To evaluate medical abortion by Domicilliary administration of mifepristone and Misoprostol by assessing efficacy and women's acceptability.Methods: This was a retrospective study of 80 patients done from Jan 2017 to Jan 2018.Women with amenorrhoea of less than or equal to 63 days are advised to self administer 200 mg Mifepristone orally at home on day1.48 hrs later, oral 800 µg Misoprostol .All women followed up on day 14 of tab.Mifepristone for abortion confirmed by usg.Results: Efficacy of regimen was 100% in gestational age up to 49 days and 95.45 % in gestational age of 50-63 days.The overall success rate was 97.5%.most of the women were ready to choose same method in future if required.Conclusion: Medical abortion was simplified by Domicile use of oral mifepristone and Misoprostol as it required less hospital visits and less supervision by trained persons.Acceptability of home selfadministration was high.Hence home administration is safe and feasible for introduction into medical abortion services in India.

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Available abstract

Objective: To evaluate medical abortion by Domicilliary administration of mifepristone and Misoprostol by assessing efficacy and women's acceptability.Methods: This was a retrospective study of 80 patients done from Jan 2017 to Jan 2018.Women with amenorrhoea of less than or equal to 63 days are advised to self administer 200 mg Mifepristone orally at home on day1.48 hrs later, oral 800 µg Misoprostol .All women followed up on day 14 of tab.Mifepristone for abortion confirmed by usg.Results: Efficacy of regimen was 100% in gestational age up to 49 days and 95.45 % in gestational age of 50-63 days.The overall success rate was 97.5%.most of the women were ready to choose same method in future if required.Conclusion: Medical abortion was simplified by Domicile use of oral mifepristone and Misoprostol as it required less hospital visits and less supervision by trained persons.Acceptability of home selfadministration was high.Hence home administration is safe and feasible for introduction into medical abortion services in India.

Key concepts: Mifepristone, Medicine, Misoprostol, Medical abortion, Obstetrics, Abortion, Gynecology, Pregnancy

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