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2018•Gastroenterology ResearchOpen access

Fatal Acute Liver Failure With Intravenous Amiodarone: A Case Report and Literature Review

Vijay Bhaskar Reddy Gayam, Mazin O. Khalid, Sumit Dahal, Pavani Reddy Garlapati, Arshpal S. Gill, Ragin Alex, Mohammad Mansour

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Abstract

Amiodarone is a drug which frequently causes elevated transaminases. However, acute liver failure has been rarely reported. Here, we present a case of fatal acute liver failure following the administration of intravenous amiodarone. It is important to be aware of this rare but potentially fatal complication of intravenous amiodarone so that it can be withdrawn immediately at the first sign of hepatic impairment.

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What this paper is about

Amiodarone is a drug which frequently causes elevated transaminases. However, acute liver failure has been rarely reported. Here, we present a case of fatal acute liver failure following the administration of intravenous amiodarone. It is important to be aware of this rare but potentially fatal complication of intravenous amiodarone so that it can be withdrawn immediately at the first sign of hepatic impairment.

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OpenAlex reports 15 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Amiodarone is a drug which frequently causes elevated transaminases. However, acute liver failure has been rarely reported. Here, we present a case of fatal acute liver failure following the administration of intravenous amiodarone. It is important to be aware of this rare but potentially fatal complication of intravenous amiodarone so that it can be withdrawn immediately at the first sign of hepatic impairment.

Key concepts: Amiodarone, Medicine, Liver failure, Complication, Liver damage, Drug, Intravenous drug, Anesthesia

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