Procalcitonin Testing to Guide Antibiotic Therapy in Acute Upper and Lower Respiratory Tract Infections
Philipp Schüetz, Yannick Wirz, Beat Müeller
Abstract
Philipp Schüetz, Yannick Wirz, Beat Müeller
Abstract
Clinical Question: Is the use of procalcitonin for guiding antibiotic decisions in patients with acute upper and lower respiratory tract infections associated with improved clinical outcomes compared with usual care? Bottom Line: Among patients with varying types and severity of acute respiratory infection, using procalcitonin to guide decisions about antibiotics is associated with lower rates of antibiotic exposure, antibiotic-related adverse effects, and mortality.
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Clinical Question: Is the use of procalcitonin for guiding antibiotic decisions in patients with acute upper and lower respiratory tract infections associated with improved clinical outcomes compared with usual care? Bottom Line: Among patients with varying types and severity of acute respiratory infection, using procalcitonin to guide decisions about antibiotics is associated with lower rates of antibiotic exposure, antibiotic-related adverse effects, and mortality.
Key concepts: Procalcitonin, Medicine, Antibiotics, Respiratory tract infections, Antibiotic therapy, Intensive care medicine, Internal medicine, Respiratory tract